Jinfeng Shen van den Bogaard, E. H. Kouwenhoven, E. N. Bykov, V. J. N. Rinne, T. Zhang, Q. Tjabringa, G. S. Gilissen, C. van Heeringen, S. J. Schalkwijk, J.
...
Published in
Proceedings of the National Academy of Sciences
p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) sy...
Jinfeng Shen E. H. van den Bogaard E. N. Kouwenhoven V. J. N. Bykov T. Rinne Q. Zhang G. S. Tjabringa C. Gilissen S. J. van Heeringen J. Schalkwijk
...
Published in
Proceedings of the National Academy of Sciences
p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) sy...
Shen, Jinfeng van den Bogaard, Ellen H Kouwenhoven, Evelyn N Bykov, Vladimir J N Rinne, Tuula Zhang, Qiang Tjabringa, Geuranne S Gilissen, Christian van Heeringen, Simon J Schalkwijk, Joost
...
Published in
Proceedings of the National Academy of Sciences of the United States of America
p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) sy...
Benjamin A. Braun Amir Marcovitz J. Gray Camp Robin Jia Gill Bejerano
Published in
Proceedings of the National Academy of Sciences
Viral outbreaks in dolphins and other Delphinoidea family members warrant investigation into the integrity of the cetacean immune system. The dynamin-like GTPase genes Myxovirus 1 (Mx1) and Mx2 defend mammals against a broad range of viral infections. Loss of Mx1 function in human and mice enhances infectivity by multiple RNA and DNA viruses, inclu...
